MACROLIDE ANTIBACTERIALS
are a group of antibacterials that cause thir therapeutic effect by inhibiting bacterial protein synthesis to varying extents. The macrolides bind to the 50S ribosomal subunit with a specific target in the 23S ribosomal RNA molecule and various ribosomal proteins.
Uses
- Ear, nose and throat infections - such as otitis media (infection of the middle ear), labyrinthitis (infection of the inner ear), sinusitis (infection of the sinuses), tonsillitis (infection of the tonsils) and laryngitis (infection of the voice box).
- Chest infections - such as pneumonia (infection of the lining of the lung), bronchitis (infection of the airways of the lung) and whooping cough.
- Skin infections - such as eczema, psoriasis or acne that has become infected.
- Mouth and dental infections - such as gingivitis (infection of the gums) and a tooth abscess (infection in the root of a tooth).
- Sexually transmitted infections - such as chlamydia.
Examples include
- azithromycin
- clarithromycin
- erythromycin
- spiramycin
- telithromycin
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