OXAZOLIDINONES

 OXAZOLIDINONE ANTIBACTERIALS

This class of antibacterials work by inhibiting protein synthesis in the cell by binding to ribosome 70s. It is a broad spectrum with activity against gram positive and mycobaterias.

Examples include;  Linezolid (Zyvox)

Metabolism- liver

Elimination- renal

Pregnancy category – C

Side effects

• Altered taste

• diarrhea

• constipation

MACROLIDE ANTIBACTERIALS

para-cervical block, leukemia, complete blood count