SULFONAMIDES

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SULFONAMDE ANTIBACTERIALS


These are antibacterial drugs that inhibits bacterial enzymes that generates bacterial cell folic acid(needed for DNA and RNA synthesis) thus stopping the replication and normal function of bacteria. This action is considered bacteriostatic.
Active against most gram positive and gram negative bacteria.

Examples include;
  • sulfamethoxazole/trimethoprim (Bactrim, Bactrim DS, Septra, Septra DS)
  • sulfasalazine (Azulfidine, Sulfazine), 
  • sulfisoxazole,


Metabolism- liver

Elimination – renal

Pregnancy category- C

Side effects
  •      dizziness
  •      lethargy
  •      diarrhea
  •      nausea
  •      vomiting
  •      headache
  •      serious skin rashes and
  •      anorexia.

AMINOGLCOSIDE ANTIBACTERIALS

Para-cervical block, leukemia, complete blood count 


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